It's Now or Never may refer to:"It's Now or Never" (song), a song by Elvis Presley, based on the aria "'O Sole Mio"
It's Now or Never , a UK gameshow which aired for one episode in 2006
It's Now or Never!, a stage comedy by Miles Tredinnick
It's Now or Never (album), by the band Make Me Famous
It's Now or Never (film), a 2015 Spanish romantic comedy movie