Ace assassin Frank Kitchen is double crossed by gangsters and falls into the hands of rogue surgeon known as The Doctor who turns him into a woman. The hitman, now a hitwoman, sets out for revenge, aided by a nurse named Johnnie who also has secrets.
The Assignment is an action crime thriller film directed by Walter Hill and co-written by Hill and Denis Hamill. The film stars Michelle Rodriguez, Tony Shalhoub, Anthony LaPaglia, Caitlin Gerard, and Sigourney Weaver.