Smith, a mob informer hiding out with the Witness Protection Program, decides to make a break for it and hide out in the Arizona desert. The Feds catch up with him and rescue him just before a group of hitmen can manage to silence him for good. In the course of getting Smith away from the mafia thugs, the pair of agents assigned to protect him turn onto an abandoned stretch of highway nicknamed 'Route 666' after the mysterious death of a prison chain gang. As the three continue on their way, they soon discover just what happened to the chain gang, and how the highway earned its name.
No trailer available.
Route 666 is a 2001 action horror film directed by William Wesley and starring Lou Diamond Phillips, Lori Petty, Steven Williams, L.Q. Jones, Dale Midkiff, Alex McArthur, and Mercedes Colon. In the film, government agents are besieged by the ghosts of a massacred chain gang while driving down a desert highway.