The Hitch-Hiker is a 1953 American independent film noir thriller directed by Ida Lupino, who co-wrote it with her former husband Collier Young, and starring Edmond O'Brien, William Talman and Frank Lovejoy. Based on the 1950 killing spree of Billy Cook, the film follows two friends who are taken hostage by a serial-murdering hitchhiker during an automobile trip to Mexico.