A secretary is found dead in a White House bathroom during an international crisis, and Detective Harlan Regis is in charge of the investigation. Despite resistance from the Secret Service, Regis partners with agent Nina Chance. As political tensions rise, they learn that the crime could be part of an elaborate cover-up. Framed as traitors, the pair, plus Regis' partner, break into the White House in order to expose the true culprit.
Murder at 1600 is a 1997 American action thriller film directed by Dwight Little and written by Wayne Beach and David Hodgin. It stars Wesley Snipes, Diane Lane, Alan Alda, Daniel Benzali, Ronny Cox and Dennis Miller and follows a homicide detective who works with a secret service agent to investigate the murder of a young woman at the White House and uncover its conspiracy.